Herbicidal composition comprising glyphosate and 1-(4,6-dimethoxypyrimidin-2-yl)-3-(3-trifluoromethyl-2-pyridylsulfonyl)urea

ABSTRACT

A herbicidal composition is disclosed, comprising, as active ingredients, 1-(4,6-dimethoxypyrimidin-2-yl)-3-(3-trifluoromethyl-2-pyridylsulfonyl)urea and an isopropylamine salt or trimethylsulfonium salt of N-(phosphonomethyl)glycine.

CROSS REFERENCE TO RELATED APPLICATION

This is a Continuation of application Ser. No. 07/923,529, filed Aug. 3, 1992, now abandoned, which is a Continuation-in-Part of application Ser. No. 07/757,052, filed Sep. 9, 1991, now abandoned.

FIELD OF THE INVENTION

The present invention relates to a herbicidal composition comprising, as active ingredients, 1-(4,6-dimethoxypyrimidin-2-yl)-3-(3-trifluoromethyl-2-pyridylsulfonyl)urea (hereinafter referred to as "Compound A") and an isopropylamine salt or trimethylsulfonium salt of N-(phosphonomethyl)glycine (hereinafter referred to as "Compound B").

BACKGROUND OF THE INVENTION

Many kinds of herbicides have been developed and are used nowadays. Since objects for control with a herbicide include a wide variety of weeds with a long duration of emergence, there has been a demand for development of a herbicide having a wider herbicidal spectrum, a high activity and a persistent herbicidal effect.

As a result of extensive investigations with a view to developing a herbicide with characteristics as mentioned above, the inventors of the present invention have found out that the herbicidal composition of the present invention can control a wide variety of weeds emerging in crop lands as well as non-crop lands. More specifically, it has been found out that the herbicidal effect of the herbicidal composition of the present invention is unexpectedly higher than the mere addition of the herbicidal effects of individual active ingredients and, in short, is manifested as a synergistic herbicidal effect, whereby the herbicidal composition of the present invention may be applied in smaller amounts of the active ingredients with an expanded herbicidal spectrum and a persistent herbicidal effect as compared with any one of the individual active ingredients when singly applied. Thus, the present invention has been completed.

SUMMARY OF THE INVENTION

An object of the present invention is to provide a herbicidal composition comprising, as active ingredients, Compound A and an isopropylamine salt or trimethylsulfonium salt of Compound B.

BRIEF DESCRIPTION OF THE DRAWING

FIG. 1 is a graph showing the results of the herbicidal effect in Test Example 4.

DETAILED DESCRIPTION OF THE INVENTION

The amount of the isopropylamine salt or trimethylsulfonium salt of Compound B as one of the active ingredients of the herbicidal composition of the present invention, relative to the amount of Compound A as another active ingredient to be mixed therewith, may be in a comparatively wide range. However, the amount of the isopropylamine salt or trimethylsulfonium salt of Compound B is usually from 1.5 to 40 parts by weight, preferably from 2.5 to 40 parts by weight, and more preferably from 2.5 to 20 parts by weight, per part by weight of Compound A.

The amount of application of the herbicidal composition of the present invention cannot be unequivocally defined because it varies depending on the mixing ratio of the active ingredients, the type of formulation, the kind of object weed, the weather condition, etc. However, it is usually employed such that from 0.01 to 5 g, preferably from 0.1 to 5 g, and more preferably from 0.2 to 3 g, per are (are (a)=100 m²), of Compound A is used in combination with from 0.1 to 40 g, preferably from 1 to 40 g, and more preferably from 2 to 20 g, per are, of the isopropylamine salt or trimethylsulfonium salt of Compound B, with a total amount of the active ingredients being from 0.11 to 45 g, preferably from 1 to 45 g, and more preferably from 2 to 23 g, per are. Where the herbicidal composition of the present invention is applied after being diluted with water, an adjuvant(s) such as a spreader may be additionally used, if desired.

The herbicidal composition of the present invention is extremely high in usefulness so that it completely exterminates a wide variety of weeds ranging from annual weeds to perennial weeds even when used in small amounts of the active ingredients. Also, when applied at the time of either pre-emergence or post-emergence of weeds, it is effective so that it can exhibit a high level of herbicidal effect when used according to either soil treatment application or foliage treatment application. Therefore, the herbicidal composition of the present invention is useful for control of weeds not only in the agricultural and horticultural fields involving upland fields, orchards, etc., but also in non-crop lands including playgrounds, vacant lots, forests, and tank yards (areas of storage tanks).

The herbicidal composition of the present invention is prepared by blending various adjuvants with Compound A and the isopropylamine salt or trimethylsulfonium salt of Compound B into a formulation such as a wettable powder, a suspension concentrate, a water-dispersible granule, a granule, a dust, a water-soluble granule, a water-soluble powder, or a soluble concentrate according to any customary method of preparing agricultural chemicals. Compound A and the isopropylamine salt or trimethylsulfonium salt of Compound B may be either mixed together and prepared into a formulation, or prepared into separate formulations and mixed together.

The above-mentioned formulations of the herbicidal composition of the present invention may contain from 1 to 98%, preferably from 1 to 95%, and more preferably from 1 to 90%, in terms of weight ratio, of the active ingredients.

Examples of the above-mentioned adjuvants include solid carriers such as diatomaceous earth, slaked lime, calcium carbonate, talc, white carbon, kaolin, bentonite, zieclite, water-soluble starch, sodiumcarbonate, sodium bicarbonate, and sodium sulfate; antifreezing agents such as ethylene glycol and propylene glycol; spreaders and surfactants such as salts of alkyl sulfates, salts of alkylbenzenesulfonates, salts of lignosulfonate, polyoxyethylene glycol alkyl ethers, polyoxyethylene lauryl ethers, polyoxyethylene alkylaryl ethers, polyoxyethylene fatty acid esters, polyoxyethylene sorbitan fatty acid esters, polyoxyethylene styrylphenyl ethers, salts of polycarboxylates, salts of dialkyl sulfosuccinates, salts of alkyl diglycol ether sulfates, salts of polyoxyethylene alkylaryl ether sulfates, salts of polyoxyethylene alkylaryl phosphates, polyoxyethylene hydrogenated castor oil, salts of styrylphenyl phosphate, and condensates of salts of napthalenesulfonate and formalin; crop oils and mineral oils such as olive oil, kapok oil, castor oil, papaya oil, camellia oil, coconut oil, sesame oil, corn oil, rice bran oil, peanut oil, cotton seed oil, soybean oil, rape seed oil, linseed oil, tung oil, and liquid paraffin; solvents such as propylene glycol monomethyl ether; thixotropic materials such as aluminum magnesium silicate and bentonite-alkylamino complexes; and thickeners such as xanthan gum. The above-mentioned adjuvants may be used in a preliminarily mixed form thereof, if desired. The herbicidal composition of the present invention, prepared in the foregoing manner, may further comprise other herbicides, insecticides, fungicides, and/or plant growth regulators incorporated thereinto.

A description will now be made of Formulation Examples of the herbicidal composition of the present invention, which are, however, not restrictive.

    ______________________________________                                         Formulation Example 1                                                          ______________________________________                                         (1) Trimethylsulfonium salt of                                                                           30     parts by weight                                   Compound B                                                                 (2) Compound A            2      parts by weight                               (3) Soybean oil           54     parts by weight                               (4) Bentonite-alkylamino complex                                                   (New D Orben ®: manufactured by                                                                  2      parts by weight                                   Shiraishi Kogyo Kaisha, Ltd.)                                              (5) Mixture of a polyoxyethylene                                                                         12     parts by weight                                   alkylaryl ether, a polyoxyethylene                                             hydrogenated castor oil, a polyoxy-                                            ethylene alkylaryl phosphate, a                                                sodium dialkyl sulfosuccinate and a                                            polyoxyethylene fatty acid ester                                               (Sorpol 3747K ®: manufactured by                                           Toho Chemical Industry Co., Ltd.)                                          ______________________________________                                    

The above-mentioned components are uniformly mixed together by a wet pulverizer to obtain an oil-based suspension concentrate.

    ______________________________________                                         Formulation Example 2                                                          ______________________________________                                         (1) Isopropylamine salt of Compound B                                                                    80     parts by weight                                   (common name: glyphosate-                                                      isopropylammonium)                                                         (2) Compound A            5      parts by weight                               (3) Surfactant of special polycarboxylic                                           acid type polymer (Demol EP ®:                                                                   8      parts by weight                                   manufactured by Kao Corporation)                                           (4) Sodium sulfate        7      parts by weight                               ______________________________________                                    

The above-mentioned components are dissolved or suspended in a three-fold amount of water and dried by a spray dryer to obtain a water-dispersible granule.

    ______________________________________                                         Formulation Example 3                                                          ______________________________________                                         (1)   Trimethylsulfonium salt of                                                                        40    parts by weight                                       Compound B                                                               (2)   Sodium salt of Compound A                                                                         2     parts by weight                                 (3)   water-soluble starch                                                                              53    parts by weight                                 (4)   Sodium lignosulfonate                                                                             5     parts by weight                                 ______________________________________                                    

The above-mentioned components are mixed together to obtain a water-soluble powder.

    ______________________________________                                         Formulation Example 4                                                          ______________________________________                                         (1) Isopropylamine salt of Compound B                                                                    2      parts by weight                                   (commone name: glyphosate-                                                     isopropylammonium)                                                         (2) Compound A            0.2    parts by weight                               (3) Calcium carbonate (fine granules)                                                                    92.8   parts by weight                               (4) Sodium dialkyl sulfosuccinate                                                                        1      part by weight                                    (Neocol YSK ®: manufactured by                                             Dai-ichi Kogyo Seiyaku Co., Ltd.)                                          (5) Polyoxyethylene octylphenyl ether                                                                    2      parts by weight                                   (Noigen EA-92 ®: manufactured by                                           Dai-ichi Kogyo Seiyaku Co., Ltd.)                                          (6) White carbon          2      parts by weight                               ______________________________________                                    

The above-mentioned components are mixed together to obtain a granule.

    ______________________________________                                         Formulation Example 5                                                          ______________________________________                                         (1) Trimethylsulfonium salt of                                                                           89    parts by weight                                    Compound B                                                                 (2) Compound A            6     parts by weight                                (3) Condensate of sodium naphthalene-                                                                    5     parts by weight                                    sulfonate and formalin (Lavelin                                                FAN ®:)                                                                ______________________________________                                    

The above-mentioned components are mixed together to obtain a wettable powder.

    ______________________________________                                         Formulation Example 6                                                          ______________________________________                                         (1) Isopropylamine salt of Compound B                                                                    82.5   parts by weight                                   (commone name: glyphosate-                                                     isopropylammonium)                                                         (2) Compound A            5.5    parts by weight                               (3) Sodium bicarbonate    7      parts by weight                               (4) Sodium alkyl sulfate (Monogen                                                                        5      parts by weight                                   Y-500 ®:)                                                              ______________________________________                                    

The above-mentioned components are mixed together to obtain a water-soluble powder.

    ______________________________________                                         Formulation Example 7                                                          ______________________________________                                         (1)  Trimethylsulfonium salt of                                                                         60     parts by weight                                     Compound B                                                                (2)  Compound A          4      parts by weight                                (3)  Sodium alkyl sulfate (Monogen                                                                      15     parts by weight                                     Y-500 ®)                                                              (4)  Calcium lignosulfonate                                                                             10     parts by weight                                (5)  Sodium sulfate      11     parts by weight                                ______________________________________                                    

The above-mentioned components are mixed together to obtain a wettable powder.

    ______________________________________                                         Formulation Example 8                                                          ______________________________________                                         (1) Isopropylamine salt of Compound B                                                                     50    parts by weight                                   (common name: glyphosphate-                                                    isopropylammonium)                                                         (2) Compound A             20    parts by weight                               (3) Sodium alkyl sulfate (Monogen                                                                         20    parts by weight                                   Y-500 ®)                                                               (4) Ammonium sulfate       10    parts by weight                               ______________________________________                                    

The above-mentioned components are mixed together to obtain a wettable powder.

The herbicidal effect of the herbicidal composition of the present invention will now be demonstrated in the following Test Examples.

Test Example 1 (Foliage Treatment Test)

Upland soil was placed in 1/10,000-are (are (a)=100 m²) pots and sown with Sorghum halepease. When the plants reached the 5 to 6-leaf stage, a predetermined amount of each herbicidal composition which had been diluted with 15 l, per are, of water and further admixed with 0.2% (v/v) of a spreader (Shin Rino®: manufactured by Nihon Nohyaku Co., Ltd.) was foliarly applied on the plants using a small spray gun. 34 days after the foliage treatment application, the fresh weight of the aerial part of the plant was measured. The above plant test was conducted at the same time under the same conditions.

The growth inhibition rate (%) given in Table 1 was calculated by the following equation (found value): ##EQU1##

In addition, the growth inhibition rate (%) calculated by the following Colby equation (calculated value) are shown in Table 1. ##EQU2##

In the above equation, α represents a growth inhibition rate (%) when treated with a (g/are) of herbicide A; β represents a growth inhibition rate (%) when treated with b (g/are) of herbicide B; and E represents an expected growth inhibition rate (%) when treated with a (g/are) of herbicide A and b (g/are) of herbicide B.

That is, if an actual growth inhibition rate (found value) is higher than the growth inhibition rate (calculated value) by the above-mentioned calculation, it can be said that the activity brought by the combination of herbicides exhibits a synergistic action.

                  TABLE 1                                                          ______________________________________                                                    Amount of Applica-                                                                         Growth Inhibition                                                  tion of Active                                                                             Rate (%)                                                           Ingredients (g/a)                                                                          Found   Calculated                                      ______________________________________                                         Compound A   0.4           85.9                                                             0.2           43.7                                                             0.1           24.9                                                Isopropylamine salt of                                                                      4.4           97.0                                                Compound B (com-                                                                            4             94.4                                                mon name: glyphos-                                                                          3             26.8                                                ateisopropyl-                                                                               2             7.0                                                 ammonium)    1             0                                                                0.5           0                                                                0.3           0.9                                                 Compound A   0.4 + 4       100     99.2                                        +            0.4 + 3       100     89.7                                        Isopropylamine salt of                                                                      0.4 + 2       100     86.9                                        Compound B (com-                                                                            0.4 + 1       100     85.9                                        mon name: glyphos-                                                                          0.2 + 4       100     96.8                                        ateisopropyl-                                                                               0.2 + 3       100     58.8                                        ammonium)    0.2 + 2       98.1    47.6                                                     0.2 + 1       99.1    43.7                                                       0.2 + 0.5   94.8    43.7                                                       0.2 + 0.3   94.8    44.2                                                     0.1 + 4       100     95.8                                                     0.1 + 3       97.6    45.0                                                     0.1 + 2       76.1    30.2                                                     0.1 +  1      96.2    24.9                                                       0.1 + 0.5   87.3    24.9                                                       0.1 + 0.3   63.8    25.6                                        ______________________________________                                    

Test Example 2 (Foliage Treatment Test)

In a field where Solidago altissima had been growing predominantly, foliage treatment application of a predetermined amount of each herbicidal composition which had been diluted with 15 l, per are, of water and further admixed with 0.05% (v/v) of a spreader (Shin Rino®) wad done using a small spray gun when the weed reached 20 to 30 cm height. Each of 9, 44 and 63 days after the foliage treatment application, the herbicidal effect of the herbicidal composition was examined through visual observation according to the following evaluation criteria. The above plant test was conducted at the same time under the same conditions. The results are shown in Table 2.

    ______________________________________                                                     Growth                                                             Rating      Inhibition Rate (%)                                                ______________________________________                                         1            0 to 19                                                           2           20 to 29                                                           3           30 to 39                                                           4           40 to 49                                                           5           50 to 59                                                           6           60 to 69                                                           7           70 to 79                                                           8           80 to 89                                                           9           90 to 99                                                           10          100                                                                ______________________________________                                    

                  TABLE 2                                                          ______________________________________                                                 Amount of                                                                      Application                                                                    of Active  Rating                                                              Ingredients (g/a)                                                                         9 DAT   44 DAT   63 DAT                                     ______________________________________                                         Compound A                                                                                1           4       4-5    4                                        Isopropylamine                                                                           20           3-4     8-9    7                                        salt of Com-                                                                   pound B                                                                        (common name:                                                                  glyphosate-                                                                    isopropyl-                                                                     ammonium)                                                                      Trimethyl-                                                                               20           3-4     7-8    6                                        sulfonium salt                                                                 of Compound B                                                                  (common name:                                                                  glyphosate-                                                                    trimesium)                                                                     Compound A +                                                                             0.5 + 10     5       9      8-9                                      Isopropylamine                                                                 salt of Com-                                                                   pound B                                                                        (common name:                                                                  glyphosate-                                                                    isopropyl-                                                                     ammonium)                                                                      Compound A +                                                                             0.5 + 10     4-5     9      8-9                                      Trimethyl-                                                                     sulfonium salt                                                                 of Compound B                                                                  (common name:                                                                  glyphosate-                                                                    trimesium)                                                                     ______________________________________                                          DAT: days after treatment                                                

Test Example 3 (Foliage Treatment Test)

Upland soil was placed in 1/10,000-are (are (a)=100 m²) pots and sown with Digitaria sanquinalis. When the plants reached the six-leaf stage, a predetermined amount of each herbicidal composition which had been diluted with 10 l, per are, of water and further admixed with 0.2% (v/v) of a spreader (Shin Rino®) was foliarly applied on the plants using a small spray gun. 27 days after the foliage treatment application, the herbicidal effect of the herbicidal composition was examined through visual observation according to the evaluation criteria shown in Test Example 2. The above plant test was conducted at the same time under the same conditions. The results are listed in Table 3.

                  TABLE 3                                                          ______________________________________                                                          Amount of Applica-                                                             tion of Active                                                                 Ingredients (g/a)                                                                          Rating                                            ______________________________________                                         Compound A         1             3                                                                0.5           3                                                                0.25          2                                             Isopropylamine salt of                                                                            5             6                                             Compound B (common name:                                                                          2.5           4                                             glyphosate-isopropylammonium)                                                  Compound A         1 + 5         8-9                                           +                    1 + 2.5     7                                             Isopropylamine salt of                                                                            0.5 + 5       8-9                                           Compound B (common name:                                                                          0.5 + 2.5     6                                             glyphosate-isopropylammonium)                                                                     0.25 + 5      8-9                                                              0.25 + 2.5    6                                             ______________________________________                                    

Test Example 4 (Foliage Treatment Test).

In a field where weeds such as Lolium multiflorum and Agropyron smithii had been growing mixedly, foliage treatment application of a predetermined amount of each herbicidal composition which had been diluted with 15 l, per are, of water and further admixed with 0.05% (v/v) of a spreader (Shin Rino®) was done using a small spray gun when the average plant height of these weeds reached 20 to 40 cm. After the foliage treatment application, the herbicidal effect of the herbicidal composition was examined periodically through visual observation according to the evaluation criteria shown in Test Example 2. The above plant test was conducted at the same time under the same conditions. The results are shown in FIG. 1. In FIG. 1, the ∘--∘ curve means the case of Compound A (amount: 0.75 g/a); the -- curve means the case of isopropylamine salt of Compound B (common name: glyphosate-isopropylammonium) (amount: 20 g/a); and the -- curve means the case of a mixture of Compound A (amount: 0.75 g/a) and isopropylamine salt of Compound B (amount: 10 g/a), respectively.

While the invention has been described in detail and with reference to specific embodiments thereof, it will be apparent to one skilled in the art that various changes and modifications can be made therein without departing from the spirit and scope thereof. 

What is claimed is:
 1. A herbicidal composition consisting essentially of as active ingredients, 1-(4,6-dimethoxypyrimidin-2-yl)-3-(3-trifluoromethyl-2-pyridylsulfonyl)urea and an isopropylamine salt or trimethylsulfonium salt of N-(phosphonomethyl)glycine in a weight ratio of from 1:1.5 to 1:40.
 2. The herbicidal composition according to claim 1, wherein the active ingredients are 1-(4,6-dimethoxypyrimidin-2-yl)-3-(3-trifluoromethyl-2-pyridylsulfonyl)urea and isopropylamine salt of N-(phosphonomethyl)glycine.
 3. The herbicidal composition according to claim 1, wherein the active ingredients are 1-(4,6-dimethoxypyrimidin-2-yl)-3-(3-trifluoromethyl-2-pyridylsulfonyl)urea and trimethylsulfonium salt of N-(phosphonomethyl)glycine.
 4. The herbicidal composition according to claim 1, wherein said herbicidal composition is adapted to apply from 0.01 to 5 g, per are, of 1-(4,6-dimethoxypyrimidin-2-yl)-3-(3-trifluoromethyl-2-pyridylsulfonyl)urea in combination with from 0.1 to 40 g, per are, of the isopropylamine salt or trimethylsulfonium salt of N-(phosphonomethyl)glycine, with the total amount of the two active ingredients being from 0.11 to 45 g per are.
 5. The herbicidal composition according to claim 1, wherein said herbicidal composition is adapted to apply from 0.1 to 5 g, per are, of 1-(4,6-dimethoxypyrimidin-2-yl)-3-(3-trifluoromethyl-2-pyridylsulfonyl)urea in combination with from 1 to 40 g, per are, of the isopropylamine salt or trimethylsulfonium salt of N-(phosphonomethyl)glycine, with the total amount of the two active ingredients being from 1 to 45 g per are.
 6. The herbicidal composition according to claim 1, wherein said herbicidal composition is adapted to apply from 0.2 to 3 g, per are, of 1-(4,6-dimethoxypyrimidin-2-yl)-3-(3-trifluoromethyl-2-pyridylsulfonyl)urea in combination with from 2 to 20 g, per are, of the isopropylamine salt or trimethylsulfonium salt of N-(phosphonomethyl)glycine, with the total amount of the two active ingredients being from 2 to 23 g per are.
 7. The herbicidal composition according to claim 1, wherein the weight ratio of 1-(4,6-dimethoxypyrimidin-2-yl)-3-(3-trifluoromethyl-2-pyridylsulfonyl)urea and the isopropylamine salt or trimethylsulfonium salt of N-(phosphonomethyl)glycine is in a range of from 1:2.5 to 1:40.
 8. The herbicidal composition according to claim 1, wherein the weight ratio of 1-(4,6-dimethoxypyrimidin-2-yl)-3-(3-trifluoromethyl-2-pyridylsulfonyl)urea and the isopropylamine salt or trimethylsulfonium salt of N-(phosphonomethyl)glycine is in a range of from 1:2.5 to 1:20.
 9. The herbicidal composition according to claim 1, wherein said herbicidal composition is adapted to be applied to an area where at least one of Sorghum halepense, Solidago altissima, Digitaria sanguinalis, Lolium multiflorum and Agropyron smithii grows.
 10. The herbicidal composition according to claim 6, wherein said herbicidal composition is adapted to be applied to an area where at least one of Sorghum halepense, Solidago altissima, Digitaria sanguinalis, Lolium multiflorum and Agropyron smithii grows. 